AT A GLANCE
Potenza uses needles and radiofrequency energy to heat tissue, whereas Rejuran is an injection of a polynucleotide-based product. They are different procedures with different risk discussions: the FDA has reported burns and scarring with certain uses of RF microneedling, and Rejuran guidance covers injection-site reactions and allergies.
How do Potenza and Rejuran compare?
| Topic | Potenza | Rejuran |
|---|---|---|
| Energy type or material | Microneedling with radiofrequency energy. | Polynucleotide-based injectable treatment. |
| Effects or risks named on this site | The October 2025 FDA device-category warning describes burns, scarring, fat loss and nerve damage with certain uses of RF microneedling; it is not specific to Jcell or a statement of Korean approval status. | Discuss injection-site reactions, product-specific risks, allergies and recovery with your clinician. |
| What to confirm at consultation | Confirm the identified skin concern, who will perform treatment and their training, and the proposed tip and treatment approach. | Confirm the proposed product, amount, treatment area, number of visits and follow-up. |
How do Potenza and Rejuran methods differ?
Potenza uses needles and RF energy to heat tissue, whereas Rejuran involves injection of a polynucleotide-based product. Cynosure describes Potenza's monopolar and bipolar modes; the tip, depth and energy settings are clinical decisions. The word needle therefore refers to different procedures in this comparison, rather than a shared treatment plan or a way to predict the same recovery.
A shared marketing term such as skin rejuvenation does not make these procedures equivalent. Ask about the method, the expected recovery and what a review would assess. The FDA has reported serious complications with certain uses of RF microneedling, including burns and scarring. Discuss that safety information and the clinician’s training when considering this category of procedure. It does not establish the suitability of any individual plan.
The October 2025 US FDA warning names burns, scarring, fat loss and nerve damage reported with certain uses of RF microneedling. It is a device-category communication, not a finding specific to Jcell or a statement of Korean approval status. Rejuran's guidance separately calls for discussion of injection-site reactions, allergies and product-specific risks. Explain earlier procedures and healing problems so the doctor can relate both risk discussions to the skin concern actually being assessed.
Which risks should I compare before choosing a method?
- What finding is each procedure intended to address?
- What are the relevant complications and how are they handled?
- Would one approach, another option or deferring treatment make more sense?
Your questions
Does a texture concern mean I should have both?
No. Ask for a separate clinical reason for each proposed procedure. Combining a device and an injection adds decisions about timing, recovery and risk.
Plan your consultation in Seoul
You do not need to choose a procedure first. Share your concern and travel dates, and ask about an English-speaking consultation.
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Last updated
Sources: FDA: RF microneedling safety communication · Jcell: Rejuran treatment information · Jcell: Potenza · Cynosure: Potenza brochure.
Use this guide to prepare your questions. Your clinician can advise you on the options appropriate for your individual needs.